Herbal medicine, Botanical medicine, phytomedicine all are synonyms, have used for medical purposes. Herbal medicine have used in the treatment and prevention of disease including diabetes has a long background as compared to conventional medicine. Mother Nature has medicinal and botanical plants to mankind; there is technical data which justify wide range in Ayurveda. There are lots of plants, herbs, fruits, roots, rhizomes, bark which posses pharmacology alterations on human being , plants like stevia rebaudiana, Momordica charentia, Syzygium cumini, Azadirachta indica, Allium cepa, allium sativum, Psidium guajava, Tinospora cordifolia, Lawsonia inermis, Panax ginseng, aloe barbadensis, Zingiber officinale, Ocimum sanctum, Plantago ispaghula, Mangifera indica, etc which are most popular remedy shows antidiabetic activity. People apparently faith on them due to lesser side effect, imposes no synergistic and antagonistic action.

Keywords:- God gifted phytochemicals, benefits over synthetic drugs, technicalities behind hypoglycemic effect, all aspects like- mechanism of action, dose, formulations.

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Numerous publications on reviews and research on niosomes have been published in the last decade. This demonstrates the interest in niosomes among researchers due to their benefits over other vesicular carrier systems. Niosomes demonstrate great potential as drug carriers due to their ability to maintain biocompatibility, biodegrade and induce minimal immune response. The primary constituents of pharmaceutical administration systems is a suitable transporter that shield the medication from swift breakdown and amplifies drug levels in the anticipated tissues. They are produced when nonionic surfactants and cholesterol self-associate in liquid facet(water based). The current review provides information on contemporary niosomal drug delivery system, preparation methodologies, characterization approaches, research, as well as niosomes as drug carriers.

Keywords:- Niosomes, novel drug delivery system, Cholesterol, Proniosomes, thin film hydration method, anti-cancer drugs

[1]. Ag Seleci D, Seleci M, Walter JG, Stahl F, Scheper T. Niosomes as nanoparticular drug carriers: fundamentals and recent applications. Journal of nanomaterials. 2016 Oct;2016.

[2]. Seleci M, Seleci DA, Joncyzk R, Stahl F, Blume C, Scheper T. Smart multifunctional nanoparticles in nanomedicine. BioNanoMaterials. 2016 May 1;17(1-2):33-41.

[3]. Mahale NB, Thakkar PD, Mali RG, Walunj DR, Chaudhari SR. Niosomes: novel sustained release nonionic stable vesicular systems—an overview. Advances in colloid and interface science. 2012 Nov 15;183:46-54.

[4]. Cosco D, Paolino D, Muzzalupo R, Celia C, Citraro R, Caponio D, Picci N, Fresta M. Novel PEG-coated niosomes based on bola-surfactant as drug carriers for 5-fluorouracil. Biomedical microdevices. 2009 Oct;11:1115-25.
[5]. Paolino D, Muzzalupo R, Ricciardi A, Celia C, Picci N, Fresta M. In vitro and in vivo evaluation of Bola-surfactant containing niosomes for transdermal delivery. Biomedical microdevices. 2007 Aug;9:421-33.

L'hypertension est une des principales causes de décès dans le monde. De nombreuses molécules et plantes sont utilisées avec succès dans sa prise en charge. Catharentus Roseus est une plante de la famille des apocynacées habituellement utilisée en médecine traditionnelle dans le traitement de nombreuses pathologies dont l'hypertension. L'objectif de la présente étude était de mettre au point des gélules à base de l'extrait aqueux de Catharentus Roseus et d'en évaluer l'activité anti hypertensive......

Keywords:- Catharentus roseus, Hypertension, L-NAME, rats, Formulation, MTA.

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Pharmaceutical research has been dedicated to advancing drug delivery methods to enhance therapeutic outcomes and patient adherence. Buccal drug delivery systems, a novel approach, leverage the oral mucosa's unique attributes to provide an alternative to traditional administration routes. This study focuses on the formulation, molecular insights, and therapeutic implications of gabapentin buccal tablets, exploring the potential of this innovative approach. By examining drug formulation, physicochemical attributes, and patient-specific factors, the study reveals the interplay that affects gabapentin buccal absorption. This research contributes to the growing understanding.....

Keywords:-Mouth dissolving Tablet, Orodispersible Tablets, gabapentin, Buccal drug delivery system

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Lactic acid bacteria (LAB) are beneficial bacteria for humans and animals. However, the sleep characteristics and functions of plant LAB in human remain unclear. Here, we isolated LAB from the jeju Aloe vera in Korea, and identified one Lactobacillus helveticus KJMA-0001(AlabTM) using matrix associated laser desorption/ionization time of flight and 16S rRNA/DNA full genome sequence analyses. AlabTM survived at pH 4.5 for 24 h. In addition, this strain survived well in simulated gastric juice of humans containing pepsin and exhibited high resistance to bile salts. Effect of AlabTM on sleep related behaviors and patterns in Drosophila melanogaster was examined in both baseline and caffeine treated conditions. Total......

Keywords:-Aloe vera; plant lactic acid bacteria; Lactobacillus helveticus; sleep inducing effect; gamma-ami- nobutyric acid activity; AlabTM

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