Current-Issue

Volume 7 ~ Issue 4,~Version 1,~April - 2017


Paper Type

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Research Paper

Title

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Role of Moringa oleifera leaf extract on silk dye waste effluent inducedhistopathotoxicity on liver and testis of Swiss albino male mice Mus musculus

Country

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India

Authors

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Serina Khatun ||, and M. C. Varma

Page No.

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01-07

Paper Index
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This work focuses primarily on the effects of Moringa oleiferaleaf extract on histopathology of silk dye effluent induced histopathotoxicity (liver & testis) in swiss albino male mice Mus musculus. The histopathological parameters have been taken an account. The mice were divided into 5 Groups i.e. Group I (Control), Group II (fed with 50% silk dye), Group III (fed with 100% silk dye), Group IV (mice fed with 50% dye treated with M. oleifera leaves powder), Group V (mice fed with 100% dye treated with M. oleifera leaves powder) have been taken for experiment. The dose of silk dye was 2ml/day to both groups II and III and M. oleifera leaf is given as per the standard dose (300mg/kg b.w) to both animals of group IV and V.Administration of silk dye waste result were demonstrated atrophy of germinal epithelial cells, basement membrane, and process of spermatogenesis in different stage in case of testis and in case of liver, enlargement of the sinusoidal space, vacuole formations in hepatocyte, infiltrations with haemorrhage in hepatic tissuebut used of Moringa oleifera leafs powder it was significantly recovered the damage tissues has been observed. This study suggested that the extract may have beneficial effect on histopathological constituents such as Liver and testis. Keywords:Moringa oleifera leaf powder, silk dye waste effluent, histopathology,liver, testis, Swiss albino male mice.
[1] Augustyniak, A; Waszkiewicz, E. and Skrzydlewska, E (2005): Preventive action of M.oleifera from changes in liver antioxidant abilities of different aged rats intoxicated with ethanol. Nutrition, 21:925-932.
[2] Chang, S.I; Jin, B; Youn, P; Park, C. and Ryu, D.Y. (2007): Arsenic induced toxicity and the protective role of ascorbic acid in mouse testis. Toxicology and Applied Pharmacology, 218(2):196-203.
[3] Drill, V.A. (1952): Hepatotoxic agents: Mechanism of action and dietary relationships. Pharmacol. Rev.4:42.
[4] Elhalwagy, M.E.A; Darwish, N.S. and Zaher, E.M. (2008): Prophylactic effect of green tea polyphenols against liver and kidney injury induced by fenitrothion insecticide. Pestic. Biochem. Phys, 91:81-89.
[5] El-Zayadi, A.R (2006): Heavy smoking and liver. World. J. Gastroenterol. 12(38):6098-6101.

 

Paper Type

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Research Paper

Title

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Speckle Tracking Ultrasound: Role in Cerebrovascular Imaging

Country

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Johnson City

Authors

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Pooja Sethi Zia Ur Rahman, MD ||, Ghulam Murtaza, MD ||, Aitzaz Bin Sultan Rai, MD

Page No.

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08-09

Paper Index
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Speckle tracking ultrasound is an emerging modality. It involves tracking of ultrasound derived speckles formed by constructive and destructive interference of ultrasound waves(1). Tracking algorithms track a set (kernel) of speckles frame by frame throughout the cardiac cycle. In this way, deformation measures like strain and strain rate are calculated. Speckle tracking ultrasound has emerging applications in the field of cerebrovascular imaging.This technique has various applications as detailedas below. Laser speckle imaging during neurosurgical procedures help measures intra-operative cortical blood flow.Monitoring of the cerebral microcirculation is crucial, because tissue viability and clinical outcome depend on restoration of blood flow to an ischemic region in a timely manner. Traditionally,intraoperative visualization of vessel perfusion is routinely accomplished by indocyanine green (ICG) video angiography and off-line transit-time calculations to predict cortical blood flow.(2). However laser speckle imaging
[1] H. Blessberger,T. Binder, NON-invasive imaging: Two dimensional speckle tracking echocardiographybasic principles. Heart 96, 2010; 716-722. [2] Laser speckle imaging allows real-time intraoperative blood flow assessment during neurosurgical procedures. Nils Hecht, Johannes Woitzik, Susanne König, Peter Hornet al .Journal of Cerebral Blood Flow & Metabolism (2013) 33, 1000–1007; doi:10.1038/jcbfm.2013.42; published online 20 March 2013 [3] Chronic monitoring of vascular progression after ischemic stroke using multiexposure speckle imaging and two-photon fluorescence microscopy.Schrandt CJ, Kazmi SM, Jones TA et al. J Cereb Blood Flow Metab. 2015 Jun;35(6):933-42.
[4] Swillens, A., Segers, P., Torp, H., &Løvstakken, L. (2010). Two-dimensional blood velocity estimation with ultrasound: speckle tracking versus crossed-beam vector Doppler based on flow simulations in a carotid bifurcation model. Ultrasonics, Ferroelectrics, and Frequency Control, IEEE Transactions on, 57(2), 327-339.
[5] Catalano, M., Lamberti-Castronuovo, A., Catalano, A., Filocamo, D., &Zimbalatti, C. (2011). Two-dimensional speckle-tracking strain imaging in the assessment of mechanical properties of carotid arteries: feasibility and comparison with conventional markers of subclinical atherosclerosis. European Heart Journal-Cardiovascular Imaging, jer078.

 

Paper Type

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Research Paper

Title

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Drain Site Abdominal Hernia: Known but Rare Complication of Abdominal Drains, a Case Report and a Review of Drain Site Complications

Country

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Sri Lanka

Authors

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M B Samarawickrama ||, R W Senavirathna ||, U I Hapuarachchi

Page No.

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10-14

Paper Index
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Drains are being used in abdominal surgery since Hippocrates time therapeutically and prohpylactically aiming to reduce morbidity and early recovery of patients. But these drains are not without complications. The complications range from simple drain site infection to drain site hernia of bowel leading to strangulation and necrosis. We report a case of drain site hernia (DSH) in a 47 year-old women who presented with obstructed large incisional hernia through a previous laparotomy scar. During surgery for the incisional hernia an incarcerated DSH was identified at her right iliac fossa region. Both herniae were repaired successfully and patient's recovery was uneventful. We reviewed the literature regarding the drain site hernia and other complications of abdominal drains. The article describes types of drains, their complications and predisposing factors for those complications and the steps to be taken for the prevention.

Key words: Abdominal Drains, Hernia, Complications, Predisposing Factors, Prevention

[1] Memon MA, Memon MI, Donohue JH. Abdominal Drains: a Brief Historical Review. Ir Med J 2001; 94:164- 166.
[2] Dr. Rahul Gupta, Dr. Ashok Kumar Gupta, Dr Dev Kumar Kasliwal, et al. Is Abdominal Drain a Double Edged Sword? SharmaIndian Journal of Basic and Applied Medical Research; March 2014: Vol.-3, Issue- 2, P.661-664
[3] A. G. Radhika, and Gita Radhakrishnan. Fallopian Tube Herniation: An Unusual Complication of Surgical Drain Lipi Sharma, Alpana Singh, Sruthi Bhaskaran. Case Reports in Obstetrics and Gynecology Volume 2012, Article ID 194350,

[4] A. Loh and P.A. Jones. Evisceration and other Complications of Abdominal Drains Postgrad Med J (1991) 67, 687 – 688.
[5] Preetha Rani Kumarprasad. Drain Site Hernias - A Rare but Recognized Complication of Surgical Drainage. A Study of their Risk Factors, Management And Prevention. University Journal of Surgery and Surgical Specialties Volume 3 Issue 2 2017